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KMID : 0352519950320020256
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Korea Univercity Medical Journal
1995 Volume.32 No. 2 p.256 ~ p.261
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A Comparative Study of the Method of Deep Sedation with Midazolam-Ketamine and Midazolam-Fentanyl for the Facial Chemical Peeling
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장성호
이혜원/임혜자/김난숙/채병국/안덕선
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Abstract
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For the facial chemical peeling with 30-50% trichloroacetic acid, deep sedation was done for the patients to lessen the perception of pain. This time the authors tried to compare midazolam (0.1mg/kg)-ketamine (1mg/kg) (ketamine group) and
midazolam
(0.1mg/kg)-fentanyl(3-4ug/kg) (fentanyl group) techniques for the sedation of the patients. total 232 patients were included in this study and 133 of them received midazolam-fentanyl and the remaining 99 received midazolam-ketamine. All the
patients in
both groups were given remaining 99 received midazolam-ketamine. All the patients in both groups were given 0.5mg/kg(initial) and 0.2mg/kg/min (continuous infusion) of esmolol for the control of tachycardia and hypertension.
@ES the results were as follows :
@EN In both groups small pox and acne scar occupied most of the portion of the cases. Recovery time was shorter in the fentanyl group (p<0.05) and frequency of dream was greater in the ketamine group (14.2%) than fentanyl group (1.5%) (p<0.006).
The
status of emotion and mood was better in the fentanyl group than the ketamine group (p=0.0026, P=4.88 E-10 respectively). The preference of the patients for anesthetic techniques made no difference in both groups. The increase in blood pressure
and
heart rate were higher in the ketamine group than those in the fentanyl group (p<0.05) and the fentanyl group revealed no change in heart rate. The decrease in arterial oxygen saturation was greater in fentanyl group (p<0.001), but the risk of
decrease
in SaO2 less than 85% is possible in both groups, so even if we choose either one anesthetic technique for the facial chemical peeling vigilant monitoring of SaO2 seems to be necessary, and further improvement in technique to block the increase
in
blood
pressure is needed.
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KEYWORD
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